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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DLAT All Species: 23.64
Human Site: Y86 Identified Species: 32.5
UniProt: P10515 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P10515 NP_001922.2 647 68997 Y86 G S P G R R Y Y S L P P H Q K
Chimpanzee Pan troglodytes XP_522180 647 68973 Y86 G S P G R R Y Y S L P P H Q K
Rhesus Macaque Macaca mulatta XP_001107013 647 68918 Y86 G S P G R R C Y S L P P H Q K
Dog Lupus familis XP_546524 647 68802 Y86 G S S G R R C Y S L P P H Q K
Cat Felis silvestris
Mouse Mus musculus Q8BMF4 642 67923 Y85 G S P S R R S Y S L P P H Q K
Rat Rattus norvegicus P08461 632 67147 Y77 G S P S R R S Y S L P P H Q K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509202 536 56600
Chicken Gallus gallus XP_417933 681 72018 C114 R F V P C R R C S L P A H Q K
Frog Xenopus laevis NP_001082239 628 66845 P71 K R W Y S L P P H Q K V P L P
Zebra Danio Brachydanio rerio NP_997832 652 69250 Y87 F S Q S M R V Y S L P P H Q K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609118 512 54233
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19749 507 53448
Sea Urchin Strong. purpuratus XP_001190217 487 52117
Poplar Tree Populus trichocarpa XP_002303212 512 55370
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q5M729 539 58449
Baker's Yeast Sacchar. cerevisiae P12695 482 51800
Red Bread Mold Neurospora crassa P20285 458 48601
Conservation
Percent
Protein Identity: 100 99.2 98.1 89.4 N.A. 85.6 85.1 N.A. 70.3 72 72.8 71.9 N.A. 42 N.A. 41.7 39.8
Protein Similarity: 100 99.2 98.6 92.8 N.A. 90.2 89.6 N.A. 74.5 78.4 82.6 78.9 N.A. 53.9 N.A. 55 54.1
P-Site Identity: 100 100 93.3 86.6 N.A. 86.6 86.6 N.A. 0 46.6 0 66.6 N.A. 0 N.A. 0 0
P-Site Similarity: 100 100 93.3 86.6 N.A. 86.6 86.6 N.A. 0 46.6 0 66.6 N.A. 0 N.A. 0 0
Percent
Protein Identity: 36.3 N.A. N.A. 38.6 33.5 36.6
Protein Similarity: 50.2 N.A. N.A. 53 48.2 48.8
P-Site Identity: 0 N.A. N.A. 0 0 0
P-Site Similarity: 0 N.A. N.A. 0 0 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 6 0 0 0 % A
% Cys: 0 0 0 0 6 0 12 6 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 6 6 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 36 0 0 24 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 6 0 0 0 48 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 6 0 0 0 0 0 0 0 0 0 6 0 0 0 48 % K
% Leu: 0 0 0 0 0 6 0 0 0 48 0 0 0 6 0 % L
% Met: 0 0 0 0 6 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 30 6 0 0 6 6 0 0 48 42 6 0 6 % P
% Gln: 0 0 6 0 0 0 0 0 0 6 0 0 0 48 0 % Q
% Arg: 6 6 0 0 36 48 6 0 0 0 0 0 0 0 0 % R
% Ser: 0 42 6 18 6 0 12 0 48 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 6 0 0 0 6 0 0 0 0 6 0 0 0 % V
% Trp: 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 6 0 0 12 42 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _